Meiklejohn Lab

Selected Publications

Temperature-Sensitive Reproduction and the Physiological and Evolutionary Potential for Mother’s Curse

KL Montooth, AS Dhawanjewar, CD Meiklejohn

ICB 2019
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Invasion of the P elements: Tolerance is not futile

CD Meiklejohn, JP Blumenstiel

PLoS Biology 2018
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RNAi Doxxes Segregation Distorters on the X

JP Blumenstiel, CD Meiklejohn

Developmental Cell 2018
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Mitochondrial Dysfunction and Infection Generate Immunity–Fecundity Tradeoffs in Drosophila

JL Buchanan, CD Meiklejohn, KL Montooth

ICB 2018
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Gene Flow Mediates the Role of Sex Chromosome Meiotic Drive During Complex Speciation

CD Meiklejohn, EL Landeen, KE Gordon, T Rzatkiewicz, SB Kingan, AJ Geneva, JP Vedanayagam, CA Muirhead, D Garrigan, DL Stern, DC Presgraves

eLIFE 2018
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Sex Chromosome-wide Transcriptional Suppresion and Compensatory Cis-Regulatory Evolution Mediate Gene Expression in the Drosophila Male Germline

EL Landeen, CA Muirhead, L Wright, CD Meiklejohn, DC Presgraves

PLoS Biology 2016
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Heterochromatin and Genetic Conflict

CD Meiklejohn

PNAS 2016
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Genome-Wide Gene Expression Effects of Sex Chromosome Imprinting in Drosophila

B Lemos, AT Branco, PP Jiang, DL Hartl, CD Meiklejohn

G3: Genes|Genomes|Genetics 2014
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The roles of cis-and trans-regulation in the evolution of regulatory incompatibilities and sexually dimorphic gene expression

CD Meiklejohn, JD Coolon, DL Hartl, PJ Wittkopp

Genome research 2014
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An Incompatibility between a Mitochondrial tRNA and Its Nuclear-Encoded tRNA Synthetase Compromises Development and Fitness in Drosophila

CD Meiklejohn, MA Holmbeck, MA Siddiq, DN Abt, DM Rand, KL Montooth

PLoS Genetics 2013
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Little Evidence for Demasculinization of the Drosophila X Chromosome among Genes Expressed in the Male Germline

CD Meiklejohn, DC Presgraves

Genome Biology and Evolution 2012
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Sex Chromosome-Specific Regulation in the Drosophila Male Germline But Little Evidence for Chromosomal Dosage Compensation or Meiotic Inactivation

CD Meiklejohn, EL Landeen, JM Cook, SB Kingan, DC Presgraves

PLoS Biology 2011
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Mitochondrial-Nuclear Epistasis Affects Fitness Within Species But Does Not Contribute to Fixed Incompatibilities Between Species of Drosophila

KL Montooth, CD Meiklejohn, DN Abt, DM Rand

Evolution 2010
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Genetic Conflict and Sex Chromosome Evolution

CD Meiklejohn, Y Tao

Trends in Ecology and Evolution 2010
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Positive and Negative Selection on the Mitochondrial Genome

CD Meiklejohn, KL Montooth, DM Rand

Trends in Genetics 2007
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A Bayesian Method for Analysing Spotted Microarray Data

CD Meiklejohn, JP Townsend

Briefings in Bioinformatics 2005
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Evolution of Proteins and Gene Expression Levels are Coupled in Drosophila and are Independently Associated with mRNA Abundance, Protein Length, and Number of Protein-Protein Interactions

B Lemos, BR Bettencourt, CD Meiklejohn, DL Hartl

Molecular Biology and Evolution 2005
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Inferring Evolutionary History through Inter-and Intraspecific DNA Sequence Comparison

CJ Parsch, CD Meiklejohn, DL Hartl

Selective Sweep 2005
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Rates of divergence in gene expression profiles of primates, mice, and flies: stabilizing selection and variability among functional categories

B Lemos, CD Meiklejohn, M Cáceres, DL Hartl

Evolution 2005
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Regulatory evolution across the protein interaction network

B Lemos, CD Meiklejohn, DL Hartl

Nature Genetics 2004
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Identification of a locus under complex positive selection in Drosophila simulans by haplotype mapping and composite-likelihood estimation

CD Meiklejohn, Y Kim, DL Hartl, J Parsch

Genetics 2004
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Rapid evolution of male-biased gene expression in Drosophila

CD Meiklejohn, J Parsch, JM Ranz, DL Hartl

PNAS 2003
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Sex-dependent Gene Expression and Evolution of the Drosophila Transcriptome

JM Ranz, CI Castillo-Davis, CD Meiklejohn, DL Hartl

Science 2003
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